There are a few possible solutions to this:
- Have 2 sets of hotkeys in the keybindings options. One for your primary weapon setup and another for your secondary.
- Have a separate set of keybinds for each weapon.
- Allow players to create new weapon-specific rules on keybinds.
I absolutely love the combat in GW2, and will have a blast playing this game regardless. But I doubt it would be difficult to find thousands of other seasoned MMO players that find this situation moderately frustrating. I think accommodating us in this would go a long way with the community.